Drivers are advised to avoid the A34 between Highclere and Speen, after a lorry was involved in a collision with the central reservation this morning (Wed).
Thames Valley Police were called to the incident at 9.59am.
One lane is closed in each direction and police are advising motorists to avoid the area.
South Central Ambulance Service (SCAS) were also called to the incident at 9.57am and sent an ambulance crew and officer who remain at the scene.
Traffic is queueing on the A34 in both directions between the A4 Bath Road junction, Newbury and A343 junction at Broad Layings.
UPDATE 2PM WED
One lane of the A34 remains closed in both directions between the Bath Road junction, Newbury and A343 junction in Broad Laying due to the earlier lorry accident and barrier repairs, with congestion back to Tot Hill Services.
According to the Highways Agency, one lane remains closed in both directions, with reduced speeds past the incident location.
Around 630 metres of barrier and 235 posts have been damaged.
Work to repair the barrier may take until tomorrow morning (Thursday)
Delays are currently, at 3.55pm, at 20 minutes, but peaked at 40 minutes this afternoon.
Drivers are advised to plan their journeys to allow extra time.