The A34 south of Newbury remains closed this evening (Wed), after an artic lorry was involved in a collision with the central reservation this morning and shed its load.
One lane of the A34 northbound also remains closed, according to Highways England.
There are delays this evening of approximately one hour southbound and 40 minutes northbound.
A diversion is in place via the A4, A339, before rejoining the A34 at Tot Hill.
Highways England advise the road is unlikely to re-open until later this evening (Wed), and not until repairs have been completed to 50m of steel barrier and 16 barrier supports are set in concrete in the central reservation.
Specialist teams were also at the scene this evening clearing up debris shed from the lorry, which left boxes flung across the road, containing flammables, organic peroxides and corrosives.
This was after the lorry overturned on the A34 just after the A4 junction at Speen, with firefighters called to the scene at 6.30am.
Firefighters helped to secure bulk containers and cut away the side of the lorry, so that it could be put back on its wheels.
A Thames Valley Police (TVP) spokeswoman, Charlotte Redman, said that the driver was not thought to be injured.
Police have advised motorists to avoid the area.
(Pictures from Hampshire Roads Policing and Gill Walker)