Emergency services were called to a seven vehicle collision in Speen yesterday evening (Thurs).
Two fire engines were called from Didcot at 7.05pm to the A4.
One person was trapped.
South Central Ambulance Service (SCAS) were called at 6.22pm and sent a rapid response vehicle, ambulance and paramedic.
A 24-year-old man was taken to the Great Western Hospital in Swindon with head injuries.
Other people were assessed and treated at the scene for minor injuries.